Ethanol → N-{3-[3-tert-butyl-4-(2-morpholin-4-ylethoxy) benzylidene]-2-oxo-2,3-dihydro-1H-indol-6-yl}-acetamide

HRID 162243

Reaction equation

HRID 162243 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([CH:8]=[O:9])[cH:10][cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1.[C:22]([CH3:23])(=[O:24])[NH:25][c:26]1[cH:27][cH:28][c:29]2[c:33]([cH:34]1)[NH:32][C:31](=[O:35])[CH2:30]2.[CH2:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1.[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[CH3:48][CH2:49][OH:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([CH:8]=[C:30]2[c:29]3[cH:28][cH:27][c:26]([NH:25][C:22]([CH3:23])=[O:24])[cH:34][c:33]3[NH:32][C:31]2=[O:35])[cH:10][cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1

Participants

6

Reactant 5

HCID 702EthanolHCID 8082PiperidineHCID 8857Ethyl AcetateHCID 2749839N-(2-Oxoindolin-6-yl)acetamideHCID 225710723-Tert-butyl-4-(2-morpholin-4-ylethoxy)benzaldehyde

Product 1

HCID 53907275N-{3-[3-tert-butyl-4-(2-morpholin-4-ylethoxy) benzylidene]-2-oxo-2,3-dihydro-1H-indol-6-yl}-acetamide

Sources & evidence

ORD record
ord-724a63a923bf423f8661d531052d29a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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