Tetrahydrofuran → methyl 1-{1-[2-(7-methoxy-2,2-dimethyl-4-oxochroman-8-yl)ethyl]piperidin-4-yl}-1H-indole-6-carboxylate

Reaction equation

Cl.[NH:2]1[CH2:7][CH2:6][CH:5]([N:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([C:17]([O:19][CH3:20])=[O:18])[CH:15]=3)[CH:10]=[CH:9]2)[CH2:4][CH2:3]1.[CH3:21][O:22][C:23]1[C:32]([CH2:33][CH:34]=O)=[C:31]2[C:26]([C:27](=[O:38])[CH2:28][C:29]([CH3:37])([CH3:36])[O:30]2)=[CH:25][CH:24]=1.O1CCCC1.C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>O.C1(C)C=CC=CC=1.C(O)(=O)C>[CH3:21][O:22][C:23]1[C:32]([CH2:33][CH2:34][N:2]2[CH2:3][CH2:4][CH:5]([N:8]3[C:16]4[C:11](=[CH:12][CH:13]=[C:14]([C:17]([O:19][CH3:20])=[O:18])[CH:15]=4)[CH:10]=[CH:9]3)[CH2:6][CH2:7]2)=[C:31]2[C:26]([C:27](=[O:38])[CH2:28][C:29]([CH3:37])([CH3:36])[O:30]2)=[CH:25][CH:24]=1