Dimethylformamide → 3-(2-(tert-Butyldimethylsilyloxy)-1-fluoroethyl)benzaldehyde

HRID 164064

Reaction equation

HRID 164064 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH:8]([CH2:9][O:10][Si:11]([CH3:12])([CH3:13])[C:14]([CH3:15])([CH3:16])[CH3:17])[F:18])[cH:5][cH:6][cH:7]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:24][N:25]([CH:26]=[O:27])[CH3:28].[Li:19][CH2:20][CH2:21][CH2:22][CH3:23]>>[c:2]1([CH:26]=[O:27])[cH:3][c:4]([CH:8]([CH2:9][O:10][Si:11]([CH3:12])([CH3:13])[C:14]([CH3:15])([CH3:16])[CH3:17])[F:18])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 57989324(2-(3-Bromophenyl)-2-fluoroethoxy)(tert-butyl)dimethylsilaneHCID 178418339Butyllithium

Product 1

HCID 579892013-(2-(tert-Butyldimethylsilyloxy)-1-fluoroethyl)benzaldehyde

Sources & evidence

ORD record
ord-a09c9ae680244ff88dd2c0b727ff06be
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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