1,2-Dibromoethane → 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)ethanone

HRID 1642322

Reaction equation

HRID 1642322 reaction equation
[OH:1][C:2]1[C:7]([OH:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9](=[O:11])[CH3:10].Br[CH2:13][CH2:14]Br.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[O:8]1[C:7]2[CH:6]=[CH:5][CH:4]=[C:3]([C:9](=[O:11])[CH3:10])[C:2]=2[O:1][CH2:14][CH2:13]1

Participants

5

Reactant 3

HCID 78391,2-DibromoethaneHCID 11430Potassium CarbonateHCID 64291102',3'-Dihydroxyacetophenone

Product 1

HCID 212680521-(2,3-Dihydro-1,4-benzodioxin-5-yl)ethanone

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared by reacting 1-(2,3-dihydroxy-phenyl)-ethanone with 1,2-dibromoethane in the presence of potassium carbonate in N,N-dimethylformamide at 100° C.

Workup

  1. customPrepared
  2. customat 100° C.

Sources & evidence

ORD record
ord-7379a6974076451c8cc27a367c1e3145
Source dataset
uspto-grants-2012_02
Patent number
US08119648B2

Linked notes

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