Sodium hydride → tert-butyl {1-[2-(7-bromo-5-fluoro-2-oxoquinolin-1(2H)-yl)ethyl]piperidin-4-yl}carbamate

Reaction equation

BrC1C=C(F)C=C2C=1C=CC(=O)N2.[Br:14][C:15]1[CH:24]=[C:23]2[C:18]([CH:19]=[CH:20][C:21](=[O:25])[NH:22]2)=[C:17]([F:26])[CH:16]=1.[H-].[Na+].CS(O[CH2:34][CH2:35][N:36]1[CH2:41][CH2:40][CH:39]([NH:42][C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:38][CH2:37]1)(=O)=O.C(OC(=O)NC1CCN(CCN2C3C(=CC=C(F)C=3)N=CC2=O)CC1)(C)(C)C>C(OCC)(=O)C>[C:46]([O:45][C:43](=[O:44])[NH:42][CH:39]1[CH2:40][CH2:41][N:36]([CH2:35][CH2:34][N:22]2[C:23]3[C:18](=[C:17]([F:26])[CH:16]=[C:15]([Br:14])[CH:24]=3)[CH:19]=[CH:20][C:21]2=[O:25])[CH2:37][CH2:38]1)([CH3:49])([CH3:48])[CH3:47]