Methanol → 1-Methoxy-2-dodecanol

Reaction equation

[O:1]1[CH:3]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:2]1.[Na].[CH3:15][OH:16]>>[CH3:15][O:16][CH2:2][CH:3]([OH:1])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Participants

Reactant 3

HCID 887Methanol

HCID 178581,2-Epoxydodecane

HCID 5360545Sodium

Product 1

HCID 137094341-Methoxy-2-dodecanolYield 88%

Procedure

1,2-Epoxydodecane is reacted with sodium in methanol as in Example 1 to yield 1-methoxy-2-dodecanol as a colourless oil, bp 97° C./0.07 mbar, yield 88%.

Sources & evidence

ORD record: ord-5540b98b52c64291a7699a3c55cf2772
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05176850

Reaction notes

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