Hydroxide → 2-(6-Benzyloxy-benzoimidazol-1-yl)-4-(3-chloro-phenyl)-thiazole-5-carboxylic acid

HRID 166673

Reaction equation

HRID 166673 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7](-[c:28]2[cH:29][c:30]([Cl:34])[cH:31][cH:32][cH:33]2)[n:8][c:9](-[n:11]2[cH:12][n:13][c:14]3[c:15]2[cH:16][c:17]([O:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:18][cH:19]3)[s:10]1.[Li+:40].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[OH-:41].[OH2:42]>>[O:3]=[C:4]([OH:5])[c:6]1[c:7](-[c:28]2[cH:29][c:30]([Cl:34])[cH:31][cH:32][cH:33]2)[n:8][c:9](-[n:11]2[cH:12][n:13][c:14]3[c:15]2[cH:16][c:17]([O:20][CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:18][cH:19]3)[s:10]1

Participants

6

Reactant 5

HCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 674458212-(6-Benzyloxy-benzoimidazol-1-yl)-4-(3-chloro-phenyl)-thiazole-5-carboxylic acid ethyl ester

Product 1

HCID 674440732-(6-Benzyloxy-benzoimidazol-1-yl)-4-(3-chloro-phenyl)-thiazole-5-carboxylic acid

Sources & evidence

ORD record
ord-449c0890655b43e1abefc822285b41a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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