Lithium diisopropylamide → 3-(4-Bromo-2-chloro-benzyl)-1-(4,4-difluoro-cyclohexyl)-pyrrolidin-2-one
Reaction equation
[F:1][C:2]1([F:14])[CH2:7][CH2:6][CH:5]([N:8]2[CH2:12][CH2:11][CH2:10][C:9]2=[O:13])[CH2:4][CH2:3]1.[Li+].CC([N-]C(C)C)C.[Br:23][C:24]1[CH:29]=[CH:28][C:27]([CH2:30]Br)=[C:26]([Cl:32])[CH:25]=1>C1COCC1.CCCCCC>[Br:23][C:24]1[CH:29]=[CH:28][C:27]([CH2:30][CH:10]2[CH2:11][CH2:12][N:8]([CH:5]3[CH2:4][CH2:3][C:2]([F:1])([F:14])[CH2:7][CH2:6]3)[C:9]2=[O:13])=[C:26]([Cl:32])[CH:25]=1Participants
6
