Dimethylformamide → N-tert-butoxycarbonyl-N-(2-pyridinylmethyl)-N'-(1-(2-trimethylsilylethoxymethyl)-1H-benzimidazol-2-ylmethyl)-N'-(8-methyl-5,6,7,8-tetrahydro-8-quinolinyl)-1,4-benzenedimethanamine

HRID 168259

Reaction equation

HRID 168259 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][NH:17][C:18]2([CH3:28])[CH2:19][CH2:20][CH2:21][c:22]3[cH:23][cH:24][cH:25][n:26][c:27]32)[cH:14][cH:15]1)[CH2:29][c:30]1[n:31][cH:32][cH:33][cH:34][cH:35]1.[CH:55]([N:56]([CH:57]([CH3:58])[CH3:59])[CH2:60][CH3:61])([CH3:62])[CH3:63].[Cl:36][CH2:37][c:38]1[n:39][c:40]2[c:41]([n:42]1[CH2:43][O:44][CH2:45][CH2:46][Si:47]([CH3:48])([CH3:49])[CH3:50])[cH:51][cH:52][cH:53][cH:54]2.[O:64]=[CH:65][N:66]([CH3:67])[CH3:68]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]([CH2:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][N:17]([C:18]2([CH3:28])[CH2:19][CH2:20][CH2:21][c:22]3[cH:23][cH:24][cH:25][n:26][c:27]32)[CH2:37][c:38]2[n:39][c:40]3[c:41]([n:42]2[CH2:43][O:44][CH2:45][CH2:46][Si:47]([CH3:48])([CH3:49])[CH3:50])[cH:51][cH:52][cH:53][cH:54]3)[cH:14][cH:15]1)[CH2:29][c:30]1[n:31][cH:32][cH:33][cH:34][cH:35]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 22018645N-tert-Butoxycarbonyl-N-(2-pyridinylmethyl)-N'-(8-methyl-5,6,7,8-tetrahydro-8-quinolinyl)-1,4-benzenedimethanamineHCID 220187062-Chloromethyl-1-(2-trimethylsilylethoxymethyl)-1H-benzimidazole

Product 1

HCID 22018754N-tert-butoxycarbonyl-N-(2-pyridinylmethyl)-N'-(1-(2-trimethylsilylethoxymethyl)-1H-benzimidazol-2-ylmethyl)-N'-(8-methyl-5,6,7,8-tetrahydro-8-quinolinyl)-1,4-benzenedimethanamine

Sources & evidence

ORD record
ord-613d1d9014784b00851ce9cf014c8d30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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