3-Bromobenzonitrile → HCID 11150790, compound

HRID 1694749

Reaction equation

HRID 1694749 reaction equation
B([C:4]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:5]=1[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])(O)O.Br[C:18]1[CH:19]=[C:20]([C:24]#[N:25])[CH:21]=[CH:22][CH:23]=1>C1COCC1>[Cl:16][C:14]1[CH:13]=[CH:12][C:5]([O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])=[C:4]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([C:24]#[N:25])[CH:19]=2)[CH:15]=1

Participants

4

Reactant 2

HCID 233813-BromobenzonitrileHCID 67277298(2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid

Product 1

HCID 11150790HCID 11150790, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared by the method of example 144 step (i) using the product from example 151 step (iv), 3-bromobenzenenitrile and THF as solvent.

Sources & evidence

ORD record
ord-5f53dcf244564fc2939ffd069027c9f7
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Linked notes

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