Bicarbonate Ion → N-Cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-2H-4-pyranylmethylamine

HRID 170835

Reaction equation

HRID 170835 reaction equation
[C:35]([O:36][BH-:37]([O:38][C:39](=[O:40])[CH3:41])[O:42][C:43](=[O:44])[CH3:45])(=[O:46])[CH3:47].[CH3:59][CH2:60][O:61][C:62](=[O:63])[CH3:64].[CH:1]1([CH2:4][NH:5][c:6]2[c:7]([S:25][CH3:26])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:23][CH3:24])[cH:17][c:18]([CH3:22])[cH:19][c:20]2[CH3:21])[CH2:2][CH2:3]1.[Na+:48].[Na+:49].[O:27]1[CH2:28][CH2:29][CH:30]([CH:33]=[O:34])[CH2:31][CH2:32]1.[O:54]1[CH2:55][CH2:56][CH2:57][CH2:58]1.[OH:50][C:51](=[O:52])[O-:53]>>[CH:1]1([CH2:4][N:5]([c:6]2[c:7]([S:25][CH3:26])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:23][CH3:24])[cH:17][c:18]([CH3:22])[cH:19][c:20]2[CH3:21])[CH2:33][CH:30]2[CH2:29][CH2:28][O:27][CH2:32][CH2:31]2)[CH2:2][CH2:3]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 2724942TriacetoxyborohydrideHCID 9964078Tetrahydro-2H-pyran-4-carboxaldehydeHCID 21984576N-cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]amine

Product 1

HCID 67220308N-Cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]-N-tetrahydro-2H-4-pyranylmethylamine

Sources & evidence

ORD record
ord-22c707f6d56d4f9e939ba907fa4be3a6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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