Hydrochloric Acid → HCID 86612752, compound
Reaction equation
[NH:1]1[C:9]2[C:4](=[C:5]([CH:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH2:11][CH2:12][NH2:13])[CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[ClH:20]>CCOC(C)=O>[ClH:20].[NH:1]1[C:9]2[C:4](=[C:5]([CH:10]([C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH2:11][CH2:12][NH2:13])[CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a stirring solution of the amine (III) (0.14 g, 0.56 mmol) in EtOAc (5 ml) was added a solution of HCl (2 M in Et2O, 0.28 ml). The mixture was concentrated in vacuo affording the hydrochloride salt (IV) as a brown solid (0.16 g, quantitative yield).
Workup
- concentrationThe mixture was concentrated in vacuo
Sources & evidence
- ORD record
- ord-fb87d5339baa4144a7c7b26f3c0bfa01
- Source dataset
- uspto-grants-2010_09
- Patent number
- US07803830B2
Reaction notes
Loading…