Benzene → Methyl 5-isopropoxynicotinate

HRID 172381

Reaction equation

HRID 172381 reaction equation
[CH3:20][O:21][C:22]([c:23]1[cH:24][n:25][cH:26][c:27]([OH:29])[cH:28]1)=[O:30].[CH:16]([CH3:17])([CH3:18])[OH:19].[CH:1]1([N:2]=[C:3]=[N:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]2)[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]1.[CH:37]([Cl:38])([Cl:39])[Cl:40].[Cu:41][Cl:42].[cH:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[CH:16]([CH3:17])([CH3:18])[O:19][c:27]1[cH:26][n:25][cH:24][c:23]([C:22]([O:21][CH3:20])=[O:30])[cH:28]1

Participants

7

Reactant 6

HCID 241BenzeneHCID 3776IsopropanolHCID 6212ChloroformHCID 10868DicyclohexylcarbodiimideHCID 62652Cuprous chlorideHCID 354317Methyl 5-hydroxypyridine-3-carboxylate

Product 1

HCID 68956521Methyl 5-isopropoxynicotinate

Sources & evidence

ORD record
ord-6151d51813824cd091c1eb6a041560ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…