Bromide ion → (5,6-Bis-benzyloxy-1H-indol-3-yl)-(2,2,3,3-tetramethyl-cyclopropyl)-methanone

HRID 174051Notes

Reaction equation

HRID 174051 reaction equation
[Br-:26].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[cH:12][cH:13][nH:14][c:15]2[cH:16][c:17]1[O:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[CH2:27]([Mg+:28])[CH3:29].[CH3:30][C:31]1([CH3:39])[CH:32]([C:36](=[O:37])[Cl:38])[C:33]1([CH3:34])[CH3:35].[Cl-:43].[Cl-:45].[Cl:40][CH2:41][Cl:42].[Zn+2:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:12]([C:36]([CH:32]3[C:31]([CH3:30])([CH3:39])[C:33]3([CH3:34])[CH3:35])=[O:37])[cH:13][nH:14][c:15]2[cH:16][c:17]1[O:18][CH2:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1

Participants

8

Reactant 7

HCID 259Bromide ionHCID 312Chloride2×HCID 6344DichloromethaneHCID 209205,6-Bis(phenylmethoxy)-1H-indoleHCID 32051Zinc(2+)HCID 110410022,2,3,3-Tetramethylcyclopropane-1-carbonyl chlorideHCID 178461628HCID 178461628, compound

Product 1

HCID 67269830(5,6-Bis-benzyloxy-1H-indol-3-yl)-(2,2,3,3-tetramethyl-cyclopropyl)-methanone

Sources & evidence

ORD record
ord-d86efdd5ffb64d72b2b24a630446dcf3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…