Water → 5-chloro-N-((1-(4-iodophenyl)-1H-pyrazol-4-yl)methyl)thiophene-2-carboxamide
Reaction equation
[CH3:25][CH2:26][O:27][C:28]([CH3:29])=[O:30].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[OH:9])[s:6]1.[I:10][c:11]1[cH:12][cH:13][c:14](-[n:17]2[n:18][cH:19][c:20]([CH2:22][NH2:23])[cH:21]2)[cH:15][cH:16]1.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[OH2:24]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:9])[NH:23][CH2:22][c:20]2[cH:19][n:18][n:17](-[c:14]3[cH:13][cH:12][c:11]([I:10])[cH:16][cH:15]3)[cH:21]2)[s:6]1Participants
6
Sources & evidence
- ORD record
- ord-936d34abdccd45438fa91ba3120c2014
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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