Methyl iodide → 4-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

HRID 174870

Reaction equation

HRID 174870 reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:12][Si:13]([CH3:14])([CH3:15])[N-:16][Si:17]([CH3:18])([CH3:19])[CH3:20].[CH3:22][I:23].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[NH:8][C:9](=[O:11])[CH2:10]2.[Li+:21]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[NH:8][C:9](=[O:11])[CH:10]2[CH3:12]

Participants

6

Reactant 5

HCID 6328Methyl iodideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 3280088Npc316347HCID 120958704-chloro-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one

Product 1

HCID 593224534-Chloro-5-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one

Sources & evidence

ORD record
ord-ff77f4f792bb4bad866a9de762d95118
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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