HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

m-Chloroperbenzoic acid → 1-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]-3-heptanone ethylene ketal

HRID 1758158
Notes
Print preview

Reaction equation

HRID 1758158 reaction equation
[CH2:1]1[O:33][C:4]2([CH2:9][CH2:8][CH:7]=[C:6]([C:10]3[CH:15]=[CH:14][C:13]([C:16]([CH3:24])([CH3:23])[CH2:17]CCCCC)=[CH:12][C:11]=3[O:25][CH2:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH2:5]2)[O:3][CH2:2]1.[C:34](=O)(O)[O-].[Na+].Cl[C:40]1[CH:45]=[CH:44]C=[C:42](C(OO)=O)[CH:41]=1>ClCCl>[CH2:2]1[O:3][C:4]([CH2:9][CH2:8][CH2:7][CH3:34])([CH2:5][CH2:6][C:10]2[CH:15]=[CH:14][C:13]([C:16]([CH3:24])([CH3:23])[CH2:17][CH2:42][CH2:41][CH2:40][CH2:45][CH3:44])=[CH:12][C:11]=2[O:25][CH2:26][C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[O:33][CH2:1]1
ParticipantsConditionsProcedureWorkupSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 70297m-Chloroperbenzoic acidHCID 516892Sodium BicarbonateHCID 572072353-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]cyclohex-3-en-1-one ethylene ketal

Product 1

HCID 867387841-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]-3-heptanone ethylene ketal

Reagents, catalysts & solvents 1

HCID 6344Dichloromethane
Solvent

Conditions

Temperature
0 °C

Procedure

To a 0° C. solution of 5.0 g. (11.2 mmole) of 3-[2-benzyloxy-4-(1,1-dimethylheptyl)phenyl]cyclohex-3-en-1-one ethylene ketal in 15 ml. of dichloromethane is added 1.26 g. (15 mmole) of sodium bicarbonate and 2.58 g. (15 mmole) of m-chloroperbenzoic acid. The reaction is stirred overnight at 0° C. and then filtered. The filtrate is diluted with 200 ml. of ether and washed with two 100 ml. portions of saturated sodium bicarbonate. The organic extract is dried over magnesium sulfate and evaporated to yield the title compound.

Workup

  1. customTo a 0° C.
  2. filtrationfiltered
  3. additionThe filtrate is diluted with 200 ml
  4. washof ether and washed with two 100 ml
  5. extractionThe organic extract
  6. dry with materialis dried over magnesium sulfate
  7. customevaporated

Sources & evidence

ORD record
ord-f65975bcdef546b19d76e93eb4be11b2
Source dataset
uspto-grants-1983_02
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04371720

Reaction notes

Loading…

On this pageParticipantsConditionsProcedureWorkupSources & evidenceReaction notes