Dimethyl Sulfoxide → tert-butyl N-methyl-N-(3-oxopropyl)carbamate

Reaction equation

[CH3:1][S:2]([CH3:3])=[O:4].[CH3:24][NH2:25].[Cl:26][CH2:27][Cl:28].[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10].[OH:11][CH2:12][CH2:13][CH2:14][N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23]>>[O:11]=[CH:12][CH2:13][CH2:14][N:15]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH3:23]

Participants

Reactant 5

HCID 679Dimethyl Sulfoxide

HCID 6329Methylamine

HCID 6344Dichloromethane

HCID 65578Oxalyl chloride

HCID 10375241tert-Butyl (3-hydroxypropyl)methylcarbamate

Product 1

HCID 10442454tert-butyl N-methyl-N-(3-oxopropyl)carbamate

Sources & evidence

ORD record: ord-ecf233bc42b54647acc932fb8d7b2ae6
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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