HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

m-Chloroperbenzoic acid → 1-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]-3-heptanone ethylene ketal

HRID 1762234
Notes
Print preview

Reaction equation

HRID 1762234 reaction equation
[CH2:1]1[O:33][C:4]2([CH2:9][CH2:8][CH:7]=[C:6]([C:10]3[CH:15]=[CH:14][C:13]([C:16]([CH3:24])([CH3:23])[CH2:17]CCCCC)=[CH:12][C:11]=3[O:25][CH2:26][C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)[CH2:5]2)[O:3][CH2:2]1.[C:34](=O)(O)[O-].[Na+].Cl[C:40]1[CH:45]=[CH:44]C=[C:42](C(OO)=O)[CH:41]=1>ClCCl>[CH2:2]1[O:3][C:4]([CH2:9][CH2:8][CH2:7][CH3:34])([CH2:5][CH2:6][C:10]2[CH:15]=[CH:14][C:13]([C:16]([CH3:24])([CH3:23])[CH2:17][CH2:42][CH2:41][CH2:40][CH2:45][CH3:44])=[CH:12][C:11]=2[O:25][CH2:26][C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=2)[O:33][CH2:1]1
ParticipantsConditionsProcedureWorkupSources & evidenceReaction notes

Participants

5

Reactant 3

HCID 70297m-Chloroperbenzoic acidHCID 516892Sodium BicarbonateHCID 572072353-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]cyclohex-3-en-1-one ethylene ketal

Product 1

HCID 867387841-[2-Benzyloxy-4-(1,1-dimethylheptyl)phenyl]-3-heptanone ethylene ketal

Reagents, catalysts & solvents 1

HCID 6344Dichloromethane
Solvent

Conditions

Temperature
0 °C

Procedure

To a 0° C. solution of 5.0 g. (11.2 mmole) of 3-[2-benzyloxy-4-(1,1-dimethylheptyl)phenyl]cyclohex-3-en-l-one ethylene ketal in 15 ml. of dichloromethane is added 1.26 g. (15 mmole) of sodium bicarbonate and 2.58 g. (15 mmole) of m-chloroperbenzoic acid. The reaction is stirred overnight at 0° C. and then filtered. The filtrate is diluted with 200 ml. of ether and washed with two 100 ml. portions of saturated sodium bicarbonate. The organic extract is dried over magnesium sulfate and evaporated to yield the title compound.

Workup

  1. customTo a 0° C.
  2. filtrationfiltered
  3. additionThe filtrate is diluted with 200 ml
  4. washof ether and washed with two 100 ml
  5. extractionThe organic extract
  6. dry with materialis dried over magnesium sulfate
  7. customevaporated

Sources & evidence

ORD record
ord-929e06584a7a4ae8ac3745349d163852
Source dataset
uspto-grants-1989_05
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04831059

Reaction notes

Loading…

On this pageParticipantsConditionsProcedureWorkupSources & evidenceReaction notes