Tetrahydrofuran → tert-butyl N-(1-oxopropan-2-yl)carbamate

HRID 177002

Reaction equation

HRID 177002 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH3:9])[C:10]([N:11]([O:12][CH3:13])[CH3:14])=[O:15])=[O:16].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:17][CH:18]([CH2:19][AlH:20][CH2:21][CH:22]([CH3:23])[CH3:24])[CH3:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH3:9])[CH:10]=[O:15])=[O:16]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 14487Diisobutylaluminum hydrideHCID 375613tert-Butyl 2-(methoxy(methyl)amino)-1-methyl-2-oxoethylcarbamate

Product 1

HCID 545705tert-butyl N-(1-oxopropan-2-yl)carbamate

Sources & evidence

ORD record
ord-85b53f10bbdb43f7b1840e39a32d8086
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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