Hydrochloric Acid → HCID 178479489, compound
Reaction equation
COC[O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:20]=[C:19]([C:21]([NH:23][C:24]([NH2:26])=[NH:25])=[O:22])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1.[ClH:27]>C(O)(C)C>[ClH:27].[OH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:20]=[C:19]([C:21]([NH:23][C:24]([NH2:26])=[NH:25])=[O:22])[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
2-(2'-Methoxymethyloxyphenyl)quinoline-4-carbonylguanidine (0.51 g) formed in Example 51 was stirred in 24 ml (5M) of an isopropyl alcohol solution of hydrochloric acid at 70° C. for 3 hours. The reaction mixture was cooled with ice, and the precipitate was collected by filtration, and dried to obtain 0.50 g of the above-mentioned compound. m.p. 270° C. or higher