Ethyl Acetate → 3-aminomethyl-7-chloro-1-(2-chloro-phenyl)-1H-quinolin-4-one

Reaction equation

[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[N:1](=[N+:2]=[N-:3])[CH2:4][c:5]1[cH:6][n:7](-[c:17]2[c:18]([Cl:23])[cH:19][cH:20][cH:21][cH:22]2)[c:8]2[cH:9][c:10]([Cl:16])[cH:11][cH:12][c:13]2[c:14]1=[O:15].[Pt:24](=[O:25])=[O:26]>>[NH2:1][CH2:4][c:5]1[cH:6][n:7](-[c:17]2[c:18]([Cl:23])[cH:19][cH:20][cH:21][cH:22]2)[c:8]2[cH:9][c:10]([Cl:16])[cH:11][cH:12][c:13]2[c:14]1=[O:15]

Participants

Reactant 3

HCID 8857Ethyl Acetate

HCID 345198Adams' catalyst

HCID 712086763-azidomethyl-7-chloro-1-(2-chloro-phenyl)-1H-quinolin-4-one

Product 1

HCID 712085643-aminomethyl-7-chloro-1-(2-chloro-phenyl)-1H-quinolin-4-one

Sources & evidence

ORD record: ord-410ba23db3a2465e8660e03bf13e7e4b
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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