Chloride → 4-Chloro-6-(2-methylbenzyl)pyrimidine

HRID 185044

Reaction equation

HRID 185044 reaction equation
[Br:1][CH:2]([Br:3])[CH3:4].[CH3:10][c:11]1[c:12]([CH2:13][Br:14])[cH:15][cH:16][cH:17][cH:18]1.[CH3:6][SiH:7]([CH3:8])[CH3:9].[Cl-:5].[Cl:19][c:20]1[n:21][cH:22][n:23][c:24]([Cl:26])[cH:25]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[OH2:33].[Zn:32]>>[CH3:10][c:11]1[c:12]([CH2:13][c:24]2[n:23][cH:22][n:21][c:20]([Cl:19])[cH:25]2)[cH:15][cH:16][cH:17][cH:18]1

Participants

9

Reactant 8

HCID 312ChlorideHCID 962WaterHCID 6992o-Xylyl bromideHCID 8028TetrahydrofuranHCID 112011,1-DibromoethaneHCID 23994ZincHCID 70435TrimethylsilaneHCID 709434,6-Dichloropyrimidine

Product 1

HCID 225997104-Chloro-6-(2-methylbenzyl)pyrimidine

Sources & evidence

ORD record
ord-8e8c34d9dba94846a5181afb264d43f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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