Sodium ion → 1-(6-Chloro-3-pyridyl)-4-tert-butoxycarbonyl homopiperazine

HRID 185159

Reaction equation

HRID 185159 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[cH:6][n:7]1.[C:22]([Li:23])([CH3:24])([CH3:25])[CH3:26].[CH3:45][CH2:46][CH2:47][CH2:48][CH3:49].[Cl:27][N:28]1[C:29]([CH3:30])([CH3:31])[C:32](=[O:33])[N:34]([Cl:35])[C:36]1=[O:37].[Na+:39].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1.[OH-:38]>>[c:2]1([Cl:27])[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:12][CH2:13][CH2:14]2)[cH:6][n:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 961HydroxideHCID 8003PentaneHCID 8028TetrahydrofuranHCID 83601,3-Dichloro-5,5-dimethylhydantoinHCID 22478562Tert-butyl 4-(6-bromopyridin-3-yl)-1,4-diazepane-1-carboxylateHCID 178418306HCID 178418306, compound

Product 1

HCID 224784871-(6-Chloro-3-pyridyl)-4-tert-butoxycarbonyl homopiperazine

Sources & evidence

ORD record
ord-6a5a61d772b04ef9af1a7118fd5a1a1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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