Ethyl octanoate → Octanoic hydrazide

HRID 1863201

Reaction equation

HRID 1863201 reaction equation
[C:1]([O:10]CC)(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].O.[NH2:14][NH2:15]>C(O)C>[C:1]([NH:14][NH2:15])(=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 7799Ethyl octanoateHCID 24654Hydrazine hydrate (1:1)

Product 1

HCID 80556Octanoic hydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Production of the spacer-gel derivative: Ethyl caprylate was converted into the corresponding hydrazide by hydrazinolysis, by initially admixing 10 ml. of this ethyl ester with 10 ml. of 98% hydrazine hydrate. Ethanol (22 ml.) was added as solvent, until the reaction mixture cleared, following which the solution was left at room temperature for 15 hours. The crystallized out resulting caprylhydrazide was filtered off and washed with ice water and then with aqueous methanol (1:1) of room temperature.

Workup

  1. customThe crystallized

Sources & evidence

ORD record
ord-30a09d1cae444aae8f82551b262200ee
Source dataset
uspto-grants-1979_09
Patent number
US04168300

Linked notes

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