DL-Serine → 3-Hydroxy-2-(toluene-4-sulfonylamino)-propionic acid
Reaction equation
[NH2:1][CH:2]([C:5]([OH:7])=[O:6])[CH2:3][OH:4].[C:8]1([CH3:18])[CH:13]=[CH:12][C:11]([S:14](Cl)(=[O:16])=[O:15])=[CH:10][CH:9]=1>>[OH:4][CH2:3][CH:2]([NH:1][S:14]([C:11]1[CH:12]=[CH:13][C:8]([CH3:18])=[CH:9][CH:10]=1)(=[O:16])=[O:15])[C:5]([OH:7])=[O:6]Participants
3
Procedure
In analogy to example 2, DL-serine was reacted with 4-toluenesulfonyl chloride to give 3-hydroxy-2-(toluene-4-sulfonylamino)-propionic acid.
Sources & evidence
- ORD record
- ord-573c43830cb04120bd69d65aca049501
- Source dataset
- uspto-grants-2009_12
- Patent number
- US07625902B2
Reaction notes
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