Chloride → 5-Ethenylpyridin-2-amine

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1.[CH2:9]([CH2:10][CH2:22][CH3:23])[C:11]([Sn:12])=[C:13]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:18][CH2:19][CH2:20][CH3:21].[CH3:26][c:27]1[cH:28][c:29]([C:30]([CH3:31])([CH3:32])[CH3:33])[c:34]([OH:35])[c:36]([C:37]([CH3:38])([CH3:39])[CH3:40])[cH:41]1.[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[Cl-:25].[Li+:24]>>[c:2]1([CH:9]=[CH2:10])[cH:3][cH:4][c:5]([NH2:8])[n:6][cH:7]1

Participants

Reactant 6

HCID 312Chloride

HCID 1140Toluene

HCID 28486Lithium ion

HCID 314042,6-Di-tert-butyl-4-methylphenol

HCID 706222-Amino-5-bromopyridine

HCID 53438229Tri(butyl)vinyltin

Product 1

HCID 220320805-Ethenylpyridin-2-amine

Sources & evidence

ORD record: ord-38096872cb5e4e92b765e293b6688648
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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