Tetrahydrofuran → Diethyl 4-(ethylpropylamino)benzylacetamidomalonate

HRID 189338

Reaction equation

[CH2:1]([CH3:2])[NH:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][CH2:9][C:10](=[O:11])[NH:12][CH:13]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]1.[I:26][CH2:27][CH2:28][CH3:29].[N:30]12[CH2:31][CH2:32][CH2:33][C:34]1=[N:35][CH2:36][CH2:37][CH2:38]2.[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH2:1]([CH3:2])[N:3]([c:4]1[cH:5][cH:6][c:7]([CH2:8][CH2:9][C:10](=[O:11])[NH:12][CH:13]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]1)[CH2:27][CH2:28][CH3:29]

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 336431-Iodopropane

HCID 763491,5-Diazabicyclo(4.3.0)non-5-ene

HCID 54294942Diethyl 4-ethylaminobenzylacetamidomalonate

Product 1

HCID 53944907Diethyl 4-(ethylpropylamino)benzylacetamidomalonate

Sources & evidence

ORD record: ord-6527add7e7b540c1bae436533c80430f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Linked notes

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