proline dl-form → 3-Imidazol-1-yl-6-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-quinoline

HRID 190252

Reaction equation

HRID 190252 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([CH2:12][c:13]3[n:14][n:15][c:16]4[n:17]3[n:18][c:19]([CH3:22])[cH:20][cH:21]4)[cH:9][c:10]2[cH:11]1.[CH3:42][S:43]([CH3:44])=[O:45].[Cu:46][I:47].[K+:31].[K+:32].[O-:33][C:34]([O-:35])=[O:36].[OH:23][C:24]([CH:25]1[NH:26][CH2:27][CH2:28][CH2:29]1)=[O:30].[nH:37]1[cH:38][n:39][cH:40][cH:41]1>>[c:2]1(-[n:37]2[cH:38][n:39][cH:40][cH:41]2)[cH:3][n:4][c:5]2[cH:6][cH:7][c:8]([CH2:12][c:13]3[n:14][n:15][c:16]4[n:17]3[n:18][c:19]([CH3:22])[cH:20][cH:21]4)[cH:9][c:10]2[cH:11]1

Participants

8

Reactant 7

HCID 614proline dl-formHCID 679Dimethyl SulfoxideHCID 795ImidazoleHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 593202953-Bromo-6-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-quinoline

Product 1

HCID 593202553-Imidazol-1-yl-6-(6-methyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-quinoline

Sources & evidence

ORD record
ord-2c0da6fc5e9748c082c2ee65217c9d46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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