Methylamine → 4,6-Dichloro-n-methylpyrimidin-2-amine

Reaction equation

[CH2:12]1[O:13][CH2:14][CH2:15][CH2:16]1.[CH3:10][NH2:11].[Cl:1][c:2]1[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1>>[c:2]1([NH:11][CH3:10])[n:3][c:4]([Cl:9])[cH:5][c:6]([Cl:8])[n:7]1

Participants

Reactant 3

HCID 6329Methylamine

HCID 8028Tetrahydrofuran

HCID 773782,4,6-Trichloropyrimidine

Product 1

HCID 2598804,6-Dichloro-n-methylpyrimidin-2-amine

Sources & evidence

ORD record: ord-b2fb68900a85486f876aeb2fc14729d9
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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