Diisopropylamine → N,N-Dimethyl-3-(4-nitrophenyl)prop-2-yn-1-amine

Reaction equation

[Br:27][c:28]1[cH:29][cH:30][c:31]([N+:34](=[O:35])[O-:36])[cH:32][cH:33]1.[C:1]([P:2]([C:3]([CH3:4])([CH3:5])[CH3:6])[C:7]([CH3:8])([CH3:9])[CH3:10])([CH3:11])([CH3:12])[CH3:13].[CH3:14][N:15]([CH2:16][C:17]#[CH:18])[CH3:19].[CH:20]([NH:21][CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26].[Cu:43][I:44].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[CH3:14][N:15]([CH2:16][C:17]#[C:18][c:28]1[cH:29][cH:30][c:31]([N+:34](=[O:35])[O-:36])[cH:32][cH:33]1)[CH3:19]

Participants

Reactant 6

HCID 7912Diisopropylamine

HCID 114661-Bromo-4-nitrobenzene

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 312751,4-Dioxane

HCID 81643N,N-Dimethylpropargylamine

HCID 83681Tris(1,1-dimethylethyl)phosphine

Product 1

Sources & evidence

ORD record: ord-2441f38657204b0b90136d48f20d05db
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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