2-Methoxyethylamine → 1-[2-((R)-Indan-1-ylamino)-quinolin-6-yl]-3-(2-methoxy-ethyl)-urea
Reaction equation
[C:1](=[O:12])(OC(Cl)(Cl)Cl)OC(Cl)(Cl)Cl.[CH3:13][O:14][CH2:15][CH2:16][NH2:17].[C@H:18]1([NH:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[C:33]([NH2:38])[CH:34]=3)[N:29]=2)[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19]1>>[C@H:18]1([NH:27][C:28]2[CH:37]=[CH:36][C:35]3[C:30](=[CH:31][CH:32]=[C:33]([NH:38][C:1]([NH:17][CH2:16][CH2:15][O:14][CH3:13])=[O:12])[CH:34]=3)[N:29]=2)[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:20][CH2:19]1Participants
4
Procedure
The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 2-methoxyethylamine and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=377.5 (M+H+).
Sources & evidence
- ORD record
- ord-e16f190caaeb4014acd5ecfd83709631