Dimethylformamide → 3-Amino-7-chloro-1-cyclopropyl-6-fluoro-1H-pyrido[2,3-d]pyrimidine-2,4-dione

HRID 193766

Reaction equation

HRID 193766 reaction equation
[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[Cl:1][c:2]1[c:3]([F:17])[cH:4][c:5]2[c:6]([n:7]([CH:13]3[CH2:14][CH2:15]3)[c:8](=[O:12])[nH:9][c:10]2=[O:11])[n:16]1.[N+:19]([c:20]1[cH:21][c:22]([N+:23]([O-:24])=[O:25])[cH:26][cH:27][c:28]1[NH:29][OH:30])([O-:31])=[O:32].[Na:18].[O:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1>>[Cl:1][c:2]1[c:3]([F:17])[cH:4][c:5]2[c:6]([n:7]([CH:13]3[CH2:14][CH2:15]3)[c:8](=[O:12])[n:9]([NH2:19])[c:10]2=[O:11])[n:16]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 312751,4-DioxaneHCID 5360545SodiumHCID 5743493N-Hydroxy-2,4-dinitrobenzenamineHCID 219795017-chloro-1-cyclopropyl-6-fluoro-1H-pyrido[2,3-d]pyrimidine-2,4-dione

Product 1

HCID 219791163-Amino-7-chloro-1-cyclopropyl-6-fluoro-1H-pyrido[2,3-d]pyrimidine-2,4-dione

Sources & evidence

ORD record
ord-a3814673ae214b51b3e617faeb7ec864
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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