HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Reaction

6-Chloroindole → HCID 178419815, compound

HRID 1938025
Notes
Print preview

Reaction equation

HRID 1938025 reaction equation
CC1(C)OB(c2ccc3ncn(C4CCOCC4)c3c2)OC1(C)C.Clc1ccc2cc[nH]c2c1>C1CCOC1.CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1.Nc1ccccc1-c1[c-]cccc1.O.O=P([O-])([O-])[O-].[Cl][Pd+].[K+].[K+].[K+]>c1cc2ccc(-c3ccc4ncn(C5CCOCC5)c4c3)cc2[nH]1
ParticipantsConditionsWorkupSources & evidenceReaction notes

Participants

8

Reactant 2

HCID 871116-ChloroindoleHCID 529880091-(Tetrahydro-2H-pyran-4-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole

Product 1

HCID 178419815HCID 178419815, compoundYield 26%

Reagents, catalysts & solvents 5

HCID 62657Potassium Phosphate, TribasicReagentHCID 54727932[2-(2-Aminophenyl)phenyl]-chloro-palladium dicyclohexyl-[2-(2,4,6-triisopropylphenyl)phenyl]phosphaneCatalystHCID 962WaterSolventHCID 8028TetrahydrofuranSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
25 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-c0781594895c46a6829faf8f2876c6db
Source dataset
Pd_CN_Coupling_Informer_Library
DOI
10.1039/c5sc04751j
Original link
View source

Reaction notes

Loading…

On this pageParticipantsConditionsWorkupSources & evidenceReaction notes