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6-Chloroindole → HCID 178481197, compound

HRID 1938038
Notes
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Reaction equation

HRID 1938038 reaction equation
Clc1ccc2cc[nH]c2c1.Cn1cnc2cc(B3OC(C)(C)C(C)(C)O3)cnc21>C1CCOC1.CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1.Nc1ccccc1-c1[c-]cccc1.O.O=P([O-])([O-])[O-].[Cl][Pd+].[K+].[K+].[K+]>Cn1cnc2cc(-c3ccc4cc[nH]c4c3)cnc21
ParticipantsConditionsWorkupSources & evidenceReaction notes

Participants

8

Reactant 2

HCID 871116-ChloroindoleHCID 467367833-methyl-6-(tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-imidazo[4,5-b]pyridine

Product 1

HCID 178481197HCID 178481197, compoundYield 47%

Reagents, catalysts & solvents 5

HCID 62657Potassium Phosphate, TribasicReagentHCID 54727932[2-(2-Aminophenyl)phenyl]-chloro-palladium dicyclohexyl-[2-(2,4,6-triisopropylphenyl)phenyl]phosphaneCatalystHCID 962WaterSolventHCID 8028TetrahydrofuranSolvent2×HCID 741954,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylInternal standard

Conditions

Temperature
25 °C

Workup

  1. stirringNo procedure recorded

Sources & evidence

ORD record
ord-d78edbb29b094a44874ddb0a40ba4dac
Source dataset
Pd_CN_Coupling_Informer_Library
DOI
10.1039/c5sc04751j
Original link
View source

Reaction notes

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On this pageParticipantsConditionsWorkupSources & evidenceReaction notes