Hydrochloric Acid → HCID 66582562, compound
Reaction equation
C1(C(C2C=CC=CC=2)=[N:8][C@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[N:12]=2)C=CC=CC=1.Cl>C1COCC1>[CH3:18][O:17][C:13]1[N:12]=[C:11]([CH2:10][C@@H:9]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[NH2:8])[CH:16]=[CH:15][CH:14]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a 100-mL round-bottomed flask was added ethyl N-(diphenylmethylidene)-3-(6-methoxy-2-pyridinyl)alaninate (1.81 g, 4.66 mmol) and 5N hydrochloric acid (1.86 mL, 9.32 mmol), and THF (20 mL). The reaction mixture was stirred at room temperature for 30 min. The solvent was removed in vacuo to give crude ethyl 3-(6-methoxy-2-pyridinyl)alaninate as a light-yellow tar, which was used without purification.