Dimethylformamide → N,N,N,2,2-Pentamethylpropan-1-aminium iodide

Reaction equation

[CH2:1](N)[C:2](C)([CH3:4])[CH3:3].[CH2:7](N(CCCC)CCCC)CCC.C[I:21].[CH3:22][N:23]([CH:25]=O)[CH3:24]>>[I-:21].[CH3:22][N+:23]([CH2:25][C:2]([CH3:4])([CH3:3])[CH3:1])([CH3:7])[CH3:24]

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6328Methyl iodide

HCID 7622Tributylamine

HCID 79882Neopentylamine

Product 1

HCID 13652289N,N,N,2,2-Pentamethylpropan-1-aminium iodide

Procedure

11.51 Grams of neopentylamine (Aldrich), 48.7 grams of tributyl amine and 100 ml of DMF were mixed and cooled. 56 Grams of methyl iodide (Aldrich) were added dropwise and the reaction as carried out and worked up as in Example 1.

Workup

temperaturecooled
customthe reaction

Sources & evidence

ORD record: ord-b24055098b804e3ea5487e19d09e7b90
Source dataset: uspto-grants-1985_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04510256

Reaction notes

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