Potassium Cation → 3-Bromo-5-(difluoromethoxy)pyridine

HRID 198633

Reaction equation

HRID 198633 reaction equation
[Br:19][c:20]1[cH:21][n:22][cH:23][c:24]([OH:26])[cH:25]1.[C:1](=[O:2])([O-:3])[O-:4].[Cl:7][C:8]([C:9]([OH:10])=[O:11])([F:12])[F:13].[K+:5].[K+:6].[O:14]=[CH:15][N:16]([CH3:17])[CH3:18].[OH2:27]>>[CH:8]([F:12])([F:13])[O:26][c:24]1[cH:23][n:22][cH:21][c:20]([Br:19])[cH:25]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 66154Chlorodifluoroacetic acidHCID 5995293-Bromo-5-hydroxypyridine

Product 1

HCID 591085683-Bromo-5-(difluoromethoxy)pyridine

Sources & evidence

ORD record
ord-9d6a0c5852f14020afd5bbb7a789aef0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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