Chloroform → 2-Amino-3,5-difluoro-6-(p-methoxybenzylamino)pyridine
Reaction equation
[CH3:18][O:19][c:20]1[cH:21][cH:22][c:23]([CH2:24][NH2:25])[cH:26][cH:27]1.[CH3:1][N:2]1[CH2:3][CH2:4][CH2:5][C:6]1=[O:7].[CH:28]([Cl:29])([Cl:30])[Cl:31].[NH2:8][c:9]1[n:10][c:11]([F:17])[c:12]([F:16])[cH:13][c:14]1[F:15]>>[NH2:8][c:9]1[n:10][c:11]([NH:25][CH2:24][c:23]2[cH:22][cH:21][c:20]([O:19][CH3:18])[cH:27][cH:26]2)[c:12]([F:16])[cH:13][c:14]1[F:15]Participants
5
Sources & evidence
- ORD record
- ord-24bfc5553065437895264c5189c322a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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