Dimethylformamide → Methyl 2,6-dichloro-5-fluoronicotinate
Reaction equation
[C:16]([Cl:17])(=[O:18])[C:19]([Cl:20])=[O:21].[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[Cl:1][CH2:2][Cl:3].[Cl:4][c:5]1[c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([F:15])[c:12]([Cl:14])[n:13]1>>[CH3:2][O:9][C:7]([c:6]1[c:5]([Cl:4])[n:13][c:12]([Cl:14])[c:11]([F:15])[cH:10]1)=[O:8]Participants
5
Sources & evidence
- ORD record
- ord-328dc99956744dd584aa5e736bd6272b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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