4-(4,6-Dichloropyrimidin-2-yl)morpholine → HCID 178452113, compound
Reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:15][C:11]([CH2:13][OH:14])([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].Cl[c:16]1[n:22][c:21]([N:23]2[CH2:28][CH2:27][O:26][CH2:25][CH2:24]2)[n:20][c:18]([Cl:19])[cH:17]1>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:15][C:11]([CH2:13][O:14][c:16]2[n:22][c:21]([N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[n:20][c:18]([Cl:19])[cH:17]2)([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]Participants
6
Reactant 2
Product 1
Reagents, catalysts & solvents 3
Conditions
- Temperature
- 130 °C
Sources & evidence
- ORD record
- ord-6b8b0fd56b734c96bdf731f3e51f8018
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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