Ethanol → Tert-butyl 1-oxo-8-azaspiro(4.5)decane-8-carboxylate

HRID 200392

Reaction equation

HRID 200392 reaction equation
[CH2:31]([OH:32])[CH3:33].[CH3:1][O:2][C:3](=[O:4])[CH:5]1[C:6](=[O:22])[C:7]2([CH2:8][CH2:9]1)[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2.[Li+:23].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1.[OH-:24].[OH2:25]>>[CH2:5]1[C:6](=[O:22])[C:7]2([CH2:8][CH2:9]1)[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2

Participants

7

Reactant 6

HCID 702EthanolHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 219838978-tert-Butyl 2-methyl 1-oxo-8-azaspiro[4.5]decane-2,8-dicarboxylate

Product 1

HCID 10848487Tert-butyl 1-oxo-8-azaspiro(4.5)decane-8-carboxylate

Sources & evidence

ORD record
ord-c3d2c832fe43485abcdd85ffd30345ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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