Methyl iodide → 2,7-Dimethylbenzo[d]oxazole

HRID 2011623

Reaction equation

HRID 2011623 reaction equation
[CH3:1][c:2]1[n:10][c:9]([c:4]2[o:3]1)[cH:8][cH:7][cH:6][c:5]2B3OC(C)(C)C(C)([CH3:11])O3.CI>>[CH3:1][c:2]1[n:10][c:9]([c:4]2[o:3]1)[cH:8][cH:7][cH:6][c:5]2[CH3:11]

Participants

8

Reactant 2

HCID 6328Methyl iodideHCID 569731272-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzoxazole

Product 1

HCID 233920942,7-Dimethylbenzo[d]oxazole

Reagents, catalysts & solvents 5

HCID 962WaterReagentHCID 516892Sodium BicarbonateReagentHCID 60153068Dichloro-(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)palladium(II)CatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
65 °C

Sources & evidence

ORD record
ord-1f786981bef14c32863960e196f26525
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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