Potassium Cation → 5-Bromo-1-(4-fluoro-phenyl)-3-methyl-1H-indole

Reaction equation

[Br:12][c:13]1[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]1.[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH3:11])[cH:6][nH:7][c:8]2[cH:9][cH:10]1.[Cu:22][I:23].[K+:21].[OH-:20].[OH2:24]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([CH3:11])[cH:6][n:7](-[c:13]3[cH:14][cH:15][c:16]([F:19])[cH:17][cH:18]3)[c:8]2[cH:9][cH:10]1

Participants

Reactant 6

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 962Water

HCID 99931-Bromo-4-fluorobenzene

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 2547075-Bromo-3-methyl-1H-indole

Product 1

HCID 186794425-Bromo-1-(4-fluoro-phenyl)-3-methyl-1H-indole

Sources & evidence

ORD record: ord-c9c210762b2d4878822ad2be1514e8f4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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