(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 178452029, compound
Reaction equation
Br[c:1]1[n:9][c:8]([c:4]2[cH:3][cH:2]1)[cH:7]c[cH:6][c:5]2[C:10]#[N:11].[CH3:12][C:13]([O:16][C:17]([N:19]1[CH2:24][C@H:22]([NH2:23])[CH2:21][CH2:20]1)=[O:18])([CH3:15])[CH3:14]>>[CH3:12][C:13]([O:16][C:17]([N:19]1[CH2:24][C@H:22]([NH:23][c:4]2[cH:10][n:11][c:1]([N:9]3[CH2:6][CH2:5]O[CH2:7][CH2:8]3)[cH:2][cH:3]2)[CH2:21][CH2:20]1)=[O:18])([CH3:15])[CH3:14]Participants
6
Conditions
- Temperature
- 120 °C
Sources & evidence
- ORD record
- ord-a71dc867563e429e82faf9751942f162
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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