Ammonia → (3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol
Reaction equation
[Na+].COCCO[AlH2-]OCCOC.[NH3:1].[CH3:2][S:3]([N:6]1[CH2:12][C@H:10]([OH:11])[C:9](=O)[CH2:8][CH2:7]1)(=[O:5])=[O:4]>>[CH3:2][S:3]([N:6]1[CH2:12][C@H:10]([OH:11])[C@H:9]([NH2:1])[CH2:8][CH2:7]1)(=[O:5])=[O:4]Participants
6
Reactant 3
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-562c4da738b642e2afd96c24806bc906
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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