Ammonium Hydroxide → (3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol

HRID 2031325

Reaction equation

HRID 2031325 reaction equation
[CH3:1][S:2]([N:5]1[CH2:11][C@@H:10]([C@H:8]2[CH2:7][CH2:6]1)[O:9]2)(=[O:4])=[O:3].[NH4+:12].[OH-]>>[CH3:1][S:2]([N:5]1[CH2:11][C@@H:10]([OH:9])[C@H:8]([NH2:12])[CH2:7][CH2:6]1)(=[O:4])=[O:3]

Participants

6

Reactant 2

HCID 14923Ammonium HydroxideHCID 178504941HCID 178504941, compound

Product 1

HCID 58777604(3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol

Reagents, catalysts & solvents 3

HCID 169664Copper;dichlorideReagentHCID 73012-MethyltetrahydrofuranSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-d9801ef476bb4855a8d41714a542b80c
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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