Acetate → 2-(Ethoxymethyl)-1-(3-methoxypropyl)-7-(2-pyridin-2-ylethenyl)imidazo[4,5-c]quinolin-4-amine

HRID 203744

Reaction equation

HRID 203744 reaction equation
[Br:38][c:39]1[cH:40][cH:41][c:42]2[c:43]3[c:44]([c:45]([NH2:49])[n:46][c:47]2[cH:48]1)[n:50][c:51]([CH2:58][O:59][CH2:60][CH3:61])[n:52]3[CH2:53][CH2:54][CH2:55][O:56][CH3:57].[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH3:71][c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1.[CH:30](=[CH2:31])[c:32]1[n:33][cH:34][cH:35][cH:36][cH:37]1.[O-:63][C:64]([CH3:65])=[O:66].[O-:67][C:68]([CH3:69])=[O:70].[Pd+2:62].[c:1]1([CH3:2])[cH:3][cH:4][cH:5][cH:6][c:7]1[P:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][c:14]1[CH3:15])[c:16]1[cH:17][cH:18][cH:19][cH:20][c:21]1[CH3:22]>>[CH:30](=[CH:31][c:39]1[cH:40][cH:41][c:42]2[c:43]3[c:44]([c:45]([NH2:49])[n:46][c:47]2[cH:48]1)[n:50][c:51]([CH2:58][O:59][CH2:60][CH3:61])[n:52]3[CH2:53][CH2:54][CH2:55][O:56][CH3:57])[c:32]1[n:33][cH:34][cH:35][cH:36][cH:37]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 1140TolueneHCID 75212-VinylpyridineHCID 8471TriethylamineHCID 80271Tri-o-tolylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 219840707-bromo-2-ethoxymethyl-1-(3-methoxypropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Product 1

HCID 688177592-(Ethoxymethyl)-1-(3-methoxypropyl)-7-(2-pyridin-2-ylethenyl)imidazo[4,5-c]quinolin-4-amine

Sources & evidence

ORD record
ord-88c551d919ac45ba9e6f084403794ad4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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