Piperonal → Ilepcimide
Reaction equation
O=Cc1ccc2c(c1)OCO2.O=C(O)CC(=O)N1CCCCC1>C1COCCN1.CN(C)c1ccncc1.C1CCOC1>O=C(/C=C/c1ccc2c(c1)OCO2)N1CCCCC1Participants
6
Reactant 2
Product 1
Reagents, catalysts & solvents 3
Conditions
- Temperature
- 25 °C
Workup
- temperatureThe product mixture was cooled to 25 °C.
- filtrationFiltered through a pad of celite · Keep Organic
- wash"The celite was washed with ethyl acetate (3 x 1 mL)."
- concentrationThe filtrate was concentrated under reduced pressure
- additionA 0.07 M stock solution of the internal standard ethylene carbonate (0.70 mL in CDCl3) was added.
Sources & evidence
- ORD record
- ord-cf7aa6ded56c47588d809974808d1c23
- Source dataset
- Transfer learning optimization of 26 decarboxylative olefination reactions
Reaction notes
Loading…