2-(o-Tolylhydrazino)-2-Thiazoline → 2-(o-Tolylazo)-2-Thiazoline

HRID 2071230Notes

Reaction equation

HRID 2071230 reaction equation
[C:1]1([CH3:14])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH:7][NH:8][C:9]1[S:10][CH2:11][CH2:12][N:13]=1>[Ag]=O.C(OCC)(=O)C>[C:1]1([CH3:14])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]=[N:8][C:9]1[S:10][CH2:11][CH2:12][N:13]=1

Participants

4

Reactant 1

HCID 124050132-(o-Tolylhydrazino)-2-Thiazoline

Product 1

HCID 124050312-(o-Tolylazo)-2-Thiazoline

Reagents, catalysts & solvents 2

HCID 92152Silver(II) oxideCatalystHCID 8857Ethyl AcetateSolvent

Procedure

To a stirred solution of 8.0 g. 2-(o-tolylhydrazino)-2-thiazoline in 400 ml. of ethyl acetate is added 4.0 g. of silver oxide. The reaction mixture is stirred for 18 hours at room temperature and filtered. The filtrate is evaporated to dryness in vacuo and the residue recrystallized from aqueous ethanol affording 6.7 g. of 2-(o-tolylazo)-2-thiazoline, m.p. 79°-80° C.

Workup

  1. filtrationfiltered
  2. customThe filtrate is evaporated to dryness in vacuo
  3. customthe residue recrystallized from aqueous ethanol affording 6.7 g

Sources & evidence

ORD record
ord-b56ac91da8194ce3897a9836b425bf05
Source dataset
uspto-grants-1977_09
Patent number
US04046753

Reaction notes

Loading…